Verapamil (Calan-SR) – Uses, Side Effects, Dosage, and More

Verapamil (Calan-SR): An Effective Medication for Cardiovascular Conditions

Verapamil, also known by its brand name Calan-SR, is a medication commonly prescribed for the treatment of various cardiovascular conditions. It belongs to the class of drugs known as calcium channel blockers and is primarily used to manage high blood pressure, angina, and certain heart rhythm disorders. Verapamil works by relaxing blood vessels and improving blood flow, thereby reducing the workload on the heart and improving overall cardiac function.

How does Verapamil (Calan-SR) work?

Verapamil works by blocking the entry of calcium into the smooth muscles of the blood vessels and heart. Calcium is essential for muscle contractions, and by inhibiting its entry, Verapamil helps to relax and widen the blood vessels, reducing blood pressure. Additionally, it slows down the electrical conduction in the heart, regulating the heart’s rhythm and preventing abnormal heartbeats.

Indications for Verapamil (Calan-SR) Use

The primary indications for the use of Verapamil (Calan-SR) include:

• High blood pressure (hypertension): Verapamil is often prescribed as a first-line treatment for hypertension due to its effectiveness in reducing blood pressure.
• Angina: Verapamil helps relieve the chest pain, shortness of breath, and discomfort associated with angina by improving blood flow to the heart.
• Atrial fibrillation: Verapamil can be used to manage irregular heart rhythms, specifically atrial fibrillation, by controlling the heart rate and rhythm.
• Migraine prevention: In some cases, Verapamil may be prescribed to prevent migraines, although the exact mechanism of its effectiveness is not fully understood.

Usage, Dosage, and Considerations

When using Verapamil (Calan-SR), it is essential to follow the prescribed dosage and guidelines provided by your healthcare professional. The dosage may vary depending on the individual’s condition, medical history, and response to treatment. Verapamil is available in extended-release formulations, allowing for once-daily dosing.

It is important to note that Verapamil may interact with certain medications, herbal supplements, and substances such as grapefruit juice. Therefore, it is crucial to inform your healthcare provider of all the medications and supplements you are currently taking before starting Verapamil.

Efficacy and Safety

The efficacy and safety of Verapamil (Calan-SR) have been extensively studied in various clinical trials and real-world settings. Studies have shown that Verapamil effectively reduces blood pressure, improves exercise tolerance in patients with angina, and helps regulate heart rhythms in individuals with atrial fibrillation.

“A study published in the American Journal of Hypertension found that Verapamil was significantly more effective in lowering systolic and diastolic blood pressure compared to placebo, with minimal side effects.” – Source: American Journal of Hypertension

While Verapamil is generally safe and well-tolerated, like any medication, it can cause side effects in some individuals. Common side effects may include constipation, dizziness, headache, and nausea. If you experience any severe or persistent side effects, it is important to seek medical attention promptly.

Conclusion

Verapamil (Calan-SR) is an effective medication for managing various cardiovascular conditions, including hypertension, angina, and atrial fibrillation. Its mechanism of action involves relaxing blood vessels, improving blood flow, and regulating heart rhythms. Consult with your healthcare provider to determine if Verapamil is the right treatment option for you.

– For more information on Verapamil, visit the WebMD or Mayo Clinic websites.

2. Uses and Benefits of Verapamil (Calan-SR)

Verapamil (Calan-SR) is a medication that belongs to the calcium channel blocker class of drugs. It is primarily used to treat high blood pressure (hypertension), certain heart rhythm disorders, and angina (chest pain).

Uses:

The uses of Verapamil (Calan-SR) include:

1. Treating hypertension: Verapamil works by relaxing the blood vessels, allowing the blood to flow more easily and lowering blood pressure.
2. Managing certain heart rhythm disorders: Verapamil can help regulate abnormal heart rhythms, such as atrial fibrillation or supraventricular tachycardia.
3. Relieving angina: Verapamil helps widen the blood vessels in the heart, improving blood flow and reducing chest pain caused by angina.
4. Preventing migraines: Verapamil is sometimes prescribed for the prevention of migraines in certain individuals.

Benefits:

The benefits of Verapamil (Calan-SR) are:

• Effective in reducing blood pressure in patients with hypertension, which can help prevent complications such as stroke, heart attack, and kidney problems.
• Can help restore normal heart rhythm in individuals with certain heart rhythm disorders, improving their overall heart function and reducing the risk of complications.
• Relieves chest pain associated with angina, allowing individuals to engage in physical activities without discomfort.
• Reduces the frequency and severity of migraines in some individuals, improving their quality of life.

Verapamil should be taken as directed by a healthcare professional and the dosage may vary depending on the individual’s condition and response to the medication.

Note: Verapamil (Calan-SR) may interact with other medications and can have potential side effects. It is important to consult with a healthcare professional before starting or changing any medication regimen.

3. Use of Verapamil (Calan-SR) for the Treatment of Hypertension

Hypertension, also known as high blood pressure, is a common condition that affects millions of people worldwide. It is a chronic medical condition characterized by elevated blood pressure levels, which can lead to various complications if left untreated. Verapamil, a medication commonly prescribed to manage hypertension, has shown promising results in controlling blood pressure and reducing the risk of related complications.

What is Verapamil (Calan-SR)?

Verapamil, marketed under the brand name Calan-SR, is a calcium channel blocker that works by relaxing the blood vessels and improving blood flow. By blocking the entry of calcium into the muscles of the heart and blood vessels, Verapamil helps to lower blood pressure and reduce the workload on the heart.

How does Verapamil (Calan-SR) help in the treatment of hypertension?

Verapamil acts on the smooth muscles lining the walls of blood vessels, causing them to relax and widen. This action helps to reduce the resistance to blood flow and lower blood pressure. By effectively dilating the blood vessels, Verapamil allows the heart to work more efficiently, reducing the strain on the cardiovascular system.

This medication is often prescribed as a first-line treatment for hypertension, as it has shown significant results in reducing blood pressure. Verapamil is particularly effective in patients with concomitant conditions such as angina or irregular heart rhythm, as it helps to control these conditions as well.

Benefits of Verapamil (Calan-SR) for hypertensive patients:

1. Effective blood pressure control: Verapamil has been proven to effectively lower blood pressure levels, helping to keep them within the normal range.
2. Reduced risk of complications: By controlling blood pressure, Verapamil can help reduce the risk of complications associated with hypertension, such as heart attack, stroke, and kidney damage.
3. Improved cardiovascular function: Verapamil’s ability to relax and dilate blood vessels improves blood flow and reduces the workload on the heart, leading to improved cardiovascular function.

Side effects of Verapamil (Calan-SR):

While Verapamil is generally well-tolerated, it may cause some side effects in certain individuals, including:

• Dizziness
• Headache
• Fatigue
• Constipation
• Swelling of ankles and feet

It is important to note that these side effects are usually mild and temporary. However, if any of these side effects persist or worsen, it is essential to seek medical attention.

Conclusion:

Verapamil (Calan-SR) is a widely prescribed medication for the treatment of hypertension due to its proven efficacy in lowering blood pressure and reducing the risk of related complications. By acting as a calcium channel blocker, it helps relax blood vessels and improve blood flow, leading to improved cardiovascular function. While Verapamil may cause some mild side effects, its benefits outweigh the risks for most hypertensive patients.

Verapamil (Calan-SR)

Verapamil, also known by its brand name Calan-SR, is a medication used to treat high blood pressure (hypertension) and certain heart conditions. It belongs to a class of drugs called calcium channel blockers, which work by relaxing and widening the blood vessels, allowing for improved blood flow and lower blood pressure.

Medical Uses

Verapamil is primarily prescribed to manage high blood pressure and prevent angina (chest pain) caused by coronary artery disease. It can also be used to treat certain irregular heart rhythms, such as atrial fibrillation or atrial flutter.

How It Works

Verapamil works by blocking calcium from entering the smooth muscle cells of the heart and blood vessels. This action relaxes and widens the blood vessels, allowing more blood to flow through and reducing the workload on the heart. It also decreases the heart rate and conduction of electrical impulses in the heart, leading to a slower and more regular heartbeat.

Dosage and Administration

The specific dosage of verapamil will vary depending on the individual and their medical condition. It is typically taken orally in the form of extended-release tablets, such as Calan-SR, which are designed to release the medication slowly over time. The tablets are usually taken once or twice a day with food.

Important Information

While verapamil is generally well-tolerated, there are some important precautions and potential side effects to be aware of. It should not be taken by individuals with certain heart conditions, such as severe heart failure or heart block. Common side effects may include dizziness, headache, constipation, and nausea. Rare but serious side effects may include low blood pressure, slow heart rate, and liver problems.

Safety and Precautions

Verapamil should not be combined with certain medications, such as beta blockers, as it may lead to additive effects on heart rate and blood pressure. It should also be used with caution in individuals with liver or kidney disease, as well as those with a history of heart rhythm abnormalities. It is important to follow the instructions of a healthcare professional and report any unusual symptoms or side effects.

Research and Statistics

Several studies have shown the effectiveness of verapamil in reducing blood pressure and managing various heart conditions. For example, a study published in the Journal of the American Medical Association (JAMA) found that verapamil was effective in lowering blood pressure in individuals with hypertension. Another study published in the European Heart Journal showed the benefits of verapamil in preventing recurrence of atrial fibrillation.

For more information on verapamil and its medical uses, you can visit the official website of the American Heart Association: https://www.heart.org/en/health-topics/high-blood-pressure/changes-you-can-make-to-manage-high-blood-pressure/types-of-blood-pressure-medications

To learn more about the research studies mentioned, please refer to the following sources:

Study	Publication
Verapamil in Treatment of Hypertension	Journal of the American Medical Association (JAMA)
Verapamil for Prevention of Atrial Fibrillation Recurrence	European Heart Journal

Overall, verapamil is a commonly prescribed medication for managing high blood pressure and certain heart conditions. It provides significant benefits in improving blood flow, reducing blood pressure, and maintaining a regular heartbeat.

Verapamil (Calan-SR): A Comprehensive Overview

Verapamil, also known by its brand name Calan-SR, is a medication widely used for several medical conditions. It belongs to the class of drugs known as calcium channel blockers, and its primary purpose is to treat high blood pressure and certain heart rhythm disorders. Let’s take a closer look at this medication and its uses.

Uses of Verapamil (Calan-SR)

Verapamil (Calan-SR) is mainly prescribed for the following conditions:

1. Hypertension (High Blood Pressure): Verapamil helps lower blood pressure by relaxing the blood vessels, allowing the heart to pump blood more efficiently.
2. Angina: Verapamil helps relieve chest pain caused by reduced blood flow to the heart muscles.
3. Atrial Fibrillation and Atrial Flutter: Verapamil can be used to control irregular heart rhythms.
4. Supraventricular Tachycardia: Verapamil may be prescribed to slow down and regulate rapid heart rates.
5. Migraine Prophylaxis: Verapamil can be effective in preventing migraines and reducing their frequency.

Dosage and Administration

Verapamil (Calan-SR) is available in various forms, including tablets and extended-release capsules. The dosage and frequency of administration depend on the medical condition being treated and the individual’s response to the medication. It is crucial to follow the prescribed dosage instructions provided by a healthcare professional.

Possible Side Effects

As with any medication, verapamil (Calan-SR) can cause side effects, although not everyone experiences them. Some common side effects include:

• Constipation
• Dizziness
• Headache
• Nausea
• Fatigue
• Low blood pressure

Serious side effects are rare but may include allergic reactions, severe dizziness, irregular heartbeat, or swelling of the hands/feet. If any severe side effects occur, medical attention should be sought immediately.

Important Precautions and Interactions

Before starting verapamil (Calan-SR), it is vital to inform the healthcare provider about any existing medical conditions, ongoing treatments, and medications being taken. Verapamil may interact with other drugs, such as:

• Beta-blockers
• Digoxin
• Statins
• Antibiotics
• Antifungal medications
• Immunosuppressant drugs

It is essential to avoid grapefruit or grapefruit juice while taking verapamil, as it may increase the medication’s concentration in the bloodstream and lead to adverse effects.

Research and Statistics

According to a study published in the Journal of the American Medical Association, verapamil has shown to be effective in treating hypertension and reducing the risk of cardiovascular events. Another study published in the Journal of Headache and Pain suggests that verapamil is a useful prophylactic medication for migraines.
Statistics from the National Health and Nutrition Examination Survey (NHANES) reveal that approximately 30% of adults in the United States have hypertension, highlighting the significance of medications like verapamil in managing this condition.

Conclusion

In conclusion, verapamil (Calan-SR) is a widely used medication for the treatment of hypertension, heart rhythm disorders, angina, and migraines. It works by relaxing blood vessels and regulating heart rhythms. Like any medication, it comes with potential side effects and precautions, and its usage should be closely monitored by healthcare professionals. Verapamil has shown to be effective in various clinical studies, presenting a viable option for individuals with specific medical conditions.

6. Verapamil (Calan-SR): Uses, Side Effects, and Interactions

Verapamil, also known by its brand name Calan-SR, is a medication commonly used to treat high blood pressure, chest pain, and certain types of irregular heart rhythms. It belongs to a class of medications called calcium channel blockers, which work by relaxing the blood vessels and increasing blood flow.

Uses of Verapamil (Calan-SR)

Verapamil is primarily prescribed for the following conditions:

• High blood pressure: Verapamil helps lower blood pressure by relaxing the blood vessels, making it easier for the heart to pump blood.
• Angina (chest pain): Verapamil can help prevent episodes of chest pain by relaxing and widening the blood vessels, allowing more blood flow to the heart.
• Supraventricular tachycardia (SVT): Verapamil is often used to manage rapid heart rhythms that originate above the ventricles of the heart.
• Atrial fibrillation or atrial flutter: Verapamil may be prescribed to control heart rhythm irregularities and regulate the heart rate in certain cases.

Side Effects of Verapamil (Calan-SR)

Like any medication, verapamil can cause side effects. The most common side effects include:

• Dizziness or lightheadedness
• Headache
• Nausea or vomiting
• Constipation
• Flushing or skin rash

Less common but more serious side effects may occur. It is important to seek medical attention if you experience any of the following:

• Slow or irregular heartbeat
• Shortness of breath
• Fainting
• Severe dizziness
• Swelling of ankles or feet

Interactions with Other Medications

Verapamil may interact with other medications, potentially causing adverse effects or reducing the effectiveness of certain drugs. It is essential to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins.

Some medications that may interact with verapamil include:

• Beta-blockers: Combining verapamil with beta-blockers may cause excessive bradycardia (slow heart rate).
• Digoxin: Verapamil can increase digoxin levels in the blood, leading to toxicity.
• Statins: The combination of verapamil and statins may increase the risk of muscle damage and myopathy.
• Antidepressants: Verapamil may interact with certain antidepressant medications, such as SSRIs, resulting in serotonin syndrome.

Your healthcare provider will closely monitor your medications and adjust the dosages as necessary to minimize potential interactions and adverse effects.

Additional Information and Resources

If you would like to learn more about verapamil (Calan-SR), its uses, side effects, and interactions, please consult the following reputable sources:

• Drugs.com – Verapamil Sustained-Release Tablets
• Mayo Clinic – Verapamil (Oral Route) – Side Effects
• RxList – Verapamil

It is crucial to consult your healthcare provider or pharmacist for personalized medical advice and guidance regarding the use of verapamil.

7. Verapamil (Calan-SR): Uses, Side Effects, Dosage, and Precautions

Verapamil, commonly marketed under the brand name Calan-SR, is a medication used primarily to treat high blood pressure, chest pain (angina), and certain heart rhythm disorders. It belongs to a class of drugs called calcium channel blockers, which work by relaxing the blood vessels and reducing the heart’s workload.

Uses:

Verapamil is commonly prescribed for the following conditions:

• High blood pressure
• Chronic stable angina
• Supraventricular tachycardia
• Atrial fibrillation or atrial flutter (off-label use)

In addition to these primary uses, verapamil has also shown promising results in the treatment of migraines and cluster headaches.

Side Effects:

Like any medication, verapamil can cause side effects, although not everyone experiences them. Common side effects include:

• Constipation
• Headache
• Dizziness
• Fatigue
• Swelling in the ankles or feet

Serious side effects, although rare, may include:

• Low blood pressure
• Slow heart rate
• Heart rhythm abnormalities
• Severe allergic reactions
• Liver problems

If you experience any severe or persistent side effects, it is important to seek medical attention immediately.

Dosage:

The dosage of verapamil will vary depending on the condition being treated and individual patient factors. It is important to follow the dosage instructions provided by your healthcare provider and to not exceed the recommended dose.

For high blood pressure, a typical starting dose may be 180 mg to 240 mg per day, divided into smaller doses taken throughout the day. The dosage may be adjusted based on your blood pressure response.

For angina, the typical starting dose is 180 mg to 240 mg per day, taken in divided doses. Again, the dosage may be adjusted based on your response to the medication.

For heart rhythm disorders, the dosage may vary and should be determined by your healthcare provider.

Precautions:

There are certain precautions and considerations to keep in mind when taking verapamil:

• Inform your healthcare provider of any allergies or sensitivities you may have.
• Let your healthcare provider know about all other medications you are taking, including over-the-counter drugs and supplements.
• Be cautious when standing up from a lying or sitting position, as verapamil may cause dizziness or lightheadedness.
• Avoid grapefruit and grapefruit juice while taking verapamil, as it can increase the levels of the medication in your body.
• Inform your healthcare provider if you have liver or kidney problems, as the dosage may need to be adjusted.
• Do not suddenly stop taking verapamil without consulting your healthcare provider, as this can worsen your condition.

Always consult with your healthcare provider for personalized advice and guidance regarding the use of verapamil.

For more information, you can visit the following sources:

• MedlinePlus
• RxList
• Mayo Clinic

Category: Calan

Tags: Calan, Verapamil